AdooQ BioScience 相關產品
本公司代理 AdooQ BioScience公司，此公司設立於加利福尼亞州，為生化供應商，主要供應小分子抑制劑，包括在多個 signal pathway 中的 kinase inhibitors，如 PI3K，AKT，HDAC，MARP......等等。
| 產品種類 | |
| Recombinant Proteins | Neurotrophins |
| Polyclonal Antibodies | Growth Factors |
| Hormones | Monoclonal Antibodies |
| Natural Proteins | Viral Antigens |
| CD Antigens | Chemokines |
| Enzymes | Cytokines |
| 研究領域 | |
| Epigenetics | HDAC, PARP, JAK, Pim, Aurora Kinase, Sirtuins, Epigenetic Reader Domain, Histone Demethylases, DNA Methyltransferases |
| Apoptosis | Bcl-2 Family, Caspase, p53, TNF-α, IPA, MDM2, PERK, Survivin, RIP Kinase, ASK, c-Ret, Protein Kinase D(PKD) |
| PI3K / Akt / mTOR | Akt, PI3K, mTOR, PDK1, DNA-PK, RSK, GSK-3, AMPK, MELK |
| Protein Tyrosine Kinase | EGFR / HER2, FGFR, PDGFR, VEGFR, IGF-1R, FLT3, c-MET, ALK, Src, c-Kit, Tie-2, ...... |
| Angiogenesis | EGRF / HER2, FGFR, PDGFR, VEGFR, VDA, HIF, FLT3, ALK, BTK, FAK, Syk, Bcr-Abl |
| MAPK | MEK, ERK, p38-MAPK, JNK/c-Jun, AP-1, Raf, TOPK, MNK, ... |
| JAK / Stat | JAK, Stat, Pim, EGFR / HER2 |
| Cell Cycle | Chk, CDK, Aurora Kinase, PLK, ROCK, c-Myc, Wee1, Ras, ... |
| DNA Damage | HDAC, PARP, DNA-PK, Topoisomerase, Telomerase, ATM / ATR, DNA / RNA Synthesis (and Polymerase), ...... |
| Cytoskeleton | Microtubules, PAK, Dynamin, Integrin, Kinesin, Mps1, Gap Junction Protein |
| Cell Metabolism | Cytochrome P450, PPAR, PDE, HSP, Hydroxylases, Factor Xa |
| Autophagy Signaling | Autophagy, LRRK2, CXCR |
| Immunlogy & Inflammation | IL Receptor, COX, CCR, Toll-like Receptors, CXCR, ROS,NOS, Keap1-Nrf2, LTR, MALT, PD-1 / PD-L-1, NADPH oxidase |
| GPCR / G Protein |
5-HT Receptors, Adrenegic Receptors, Histamine Receptors, Opioid Receptors, mGluR, peptide Receptors, Smoothened Receptors, Melatonin Receptors, ...... |
| NF-kB / IkB | NF-kB, IKK / IkB, HDAC |
| TGF-β / Smad | TGF-β / Smad Inhibitors, Protein Kinase C (PKC), Protein Kinase A (PKA), ROCK |
| Neuronal Signaling | β-Amyloid, γ-Secretase, Beta-secretase (BACE), COX, GABA Receptors, NMDA Receptors, CaMK, AChR, P2X Receptor, P2Y, ...... |
| Proteases | Caspase, HCV Protease, HIV protease, DPP-4, Cysteine Protease, Aminopeptidase, Thrombin, MMP, Tyrosinase, ...... |
| Microbiology | Reverse Transcriptase, Integrase, Antifection, ...... |
| Stem Cell / Wnt | Hedgehog, Wnt, β-catenin, Casein Kinase, Hippo, ...... |
| Membrane Transporters/Ion Channels | ATPase, CFTR, Calcium Channels, Sodium Channels, Potassium Channels, SGLT, MCT, AMPA receptor, P-gp |
| Endocrinology / Hormones | Estrongen Receptors, Progesterone Receptors, GPR, 5-alpha-reductase, Pregnane X Receptors, RAAS, Aromatase, ...... |
| Transferases | Acyltransferases, Phosphorylases, Protein Prenyltransferases |
| Ubiquitin | E1 activating, E2 conjugating, E3 ligase, DUB, p97 |
| CRISPR | |
| Others | Other inhibitors, Reagents, beta-lactamase, ...... |
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